The ROSA ONE Brain System from Zimmer Biomet Robotics is a robotic-assisted platform for minimally invasive neurosurgery. Equipped with a six-degree-of-freedom robotic arm, it ensures accurate instrument guidance while avoiding critical structures. The system supports SEEG, DBS, stereotactic biopsy, and endoscopy procedures with flexible patient registration and preoperative planning options. Its integrated force torque sensor technology provides seamless surgeon-robot interaction, improving surgical speed and precision. ROSA ONE Brain adapts to individual workflows, allows bilateral procedures without repositioning, and minimizes patient preparation, making complex neurosurgical interventions safer, more efficient, and less invasive while maintaining optimal outcomes.